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Generic vs Brand
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6.2 Postmarketing Experience
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Before Using
14.3 Tadalafil Tablets 5 mg for Once Daily Use for Benign Prostatic Hyperplasia (BPH)

Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away.Some form of sexual stimulation is needed for an erection to happen with tadalafil tablets.Tadalafil tablets do not:•cure ED•increase a man’s sexual desire•protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your healthcare provider about ways to guard against sexually transmitted diseases.•serve as a male form of birth controlTadalafil tablets are only for men over the age of 18, including men with diabetes or who have undergone prostatectomy.Tadalafil Tablets for the Treatment of Symptoms of BPHBPH is a condition that happens in men, where the prostate gland enlarges which can cause urinary symptoms.Tadalafil Tablets for the Treatment of ED and Symptoms of BPHED and symptoms of BPH may happen in the same person and at the same time. Men who have both ED and symptoms of BPH may take tadalafil tablets for the treatment of both conditions.Tadalafil tablets are not for women or children.Tadalafil tablets must be used only under a healthcare provider’s care.Who Should Not Take Tadalafil Tablets?Do not take tadalafil tablets if you:•take any medicines called “nitrates”.•use recreational drugs called “poppers” like amyl nitrite and butyl nitrite.

Condition	Caution/Advice
Nitrate Use	Do not combine; risk of severe hypotension
Cardiovascular Disease	Consult doctor before use
Liver Impairment	Dose adjustment may be necessary
Recent Stroke or Heart Attack	Seek medical advice before starting therapy
Hypotension	Avoid use; blood pressure should be stable

(See “What Is The Most Important Information I Should Know About Tadalafil Tablets?”)•take any medicines called guanylate cyclase stimulators, such as riociguat.•are allergic to tadalafil tablets or ADCIRCA®, or any of its ingredients.

Generic vs Brand

Product ESCITALOPRAM / 5 mg; 10 mg; 20 mg Tablet; 10 mg/ml oral drops

Drinking too much alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.What Are The Possible Side Effects Of Tadalafil Tablets?See “What Is The Most Important Information I Should Know About Tadalafil Tablets?”The most common side effects with tadalafil tablets are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle tadalafil sale aches usually get it 12 to 24 hours after taking tadalafil tablets. Back pain and muscle aches usually go away within 2 days.Call your healthcare provider if you get any side effect that bothers you or one that does not go away.Uncommon side effects include:An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away. See the end of this leaflet for a complete list of ingredients in tadalafil tablets.

Tadalafil 5mg can be part of a comprehensive ED treatment plan.
Lifestyle changes like exercise and quitting smoking may enhance results.
Regular medical check-ups are recommended during use.

Tadalafil 5mg may interact with other medications.
Follow prescribed instructions for safe use.
Misuse can lead to serious health risks or side effects.

Only your healthcare provider and you can decide if tadalafil tablets are right for you. Before taking tadalafil tablets, tell your healthcare provider about all your medical problems, including if you:•have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your healthcare provider if it is safe for you to have sexual activity.

Product	Dosage	Quantity + Bonus	Price
Cialis Generic	2.5mg	360 + 10 Pills	260.03€ 247.65€
Cialis Generic	2.5mg	180 + 10 Pills	154.86€ 147.49€
Tadalista Super Active	20mg	180 + 20 Pills	521.59€ 496.75€
Cialis Generic	2.5mg	30 + 4 Pills	51.95€ 49.48€
Cialis Generic	60mg	10 Pills	41.22€ 39.26€
Cialis Generic	2.5mg	10 Pills	28.51€ 27.15€
Cialis Generic	40mg	270 + 10 Pills	382.19€ 363.99€
Cialis Generic	60mg	180 + 10 Pills	313.11€ 298.20€
Cialis Generic	2.5mg	60 + 4 Pills	83.43€ 79.46€
Cialis Generic	10mg	270 + 10 Pills	308.71€ 294.01€
Tadalista Super Active	20mg	60 + 8 Pills	230.32€ 219.35€
Cialis Generic	10mg	180 + 8 Pills	236.88€ 225.60€
Tadalista Super Active	20mg	10 Pills	55.64€ 52.99€
Cialis Generic	60mg	20 Pills	65.61€ 62.49€

You should not take tadalafil tablets if your healthcare provider has told you not to have sexual activity because of your health problems.•have pulmonary hypertension•have low blood pressure or have high blood pressure that is not controlled•have had a stroke•have liver problems•have kidney problems or require dialysis•have retinitis pigmentosa, a rare genetic (runs in families) eye disease•have ever had severe vision loss, including a condition called NAION•have stomach ulcers•have a bleeding problem•have a deformed penis shape or Peyronie’s disease•have had an erection that lasted more than 4 hours•have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemiaCan Other Medicines Affect Tadalafil Tablets?Tell your healthcare provider about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

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Tadalafil tablets and other medicines may affect each other.

6.2 Postmarketing Experience

Priapism must be treated as soon as possible or lasting damage can happen to your penis, including the inability to have erections.Color vision changes, such as seeing a blue tinge (shade) to objects or having difficulty telling the difference between the colors blue and green.In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including tadalafil tablets) reported a sudden decrease or loss of vision in one or both eyes. It is uncertain whether PDE5 inhibitors directly cause the vision loss. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including tadalafil tablets, and call a healthcare provider right away.Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including tadalafil tablets. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking tadalafil tablets and contact a healthcare provider right away.These are not all the possible side effects of tadalafil tablets.

Authors’ contributions

For more information, ask your healthcare provider or pharmacist.How Should I Store Tadalafil Tablets?Store tadalafil tablets at room temperature between 59oF and 86oF (15oC and 30oC).Keep tadalafil tablets and all medicines out of the reach of children.General Information About Tadalafil Tablets:Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. Always check with your healthcare provider before starting or stopping any medicines. Especially tell your healthcare provider if you take any of the following*:•medicines called nitrates (see “What Is The Most Important Information I Should Know About Tadalafil Tablets?”)•medicines called guanylate cyclase stimulators, such as riociguat (Adempas®), used to treat pulmonary hypertension•medicines called alpha blockers. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. If tadalafil tablets are taken with certain alpha blockers, tadalafil for premature ejaculation your blood pressure could suddenly drop.

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Tadalafil tablets and other medicines may affect each other. Always check with your healthcare provider before starting or stopping any medicines. Especially tell your healthcare provider if you take any of the following*:•medicines called nitrates (see “What Is The Most Important Information I Should Know About Tadalafil Tablets?”)•medicines called guanylate cyclase stimulators, such as riociguat (Adempas®), used to treat pulmonary hypertension•medicines called alpha blockers. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. If tadalafil tablets are taken with certain alpha blockers, tadalafil for premature ejaculation your blood pressure could suddenly drop.

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You could get dizzy or faint.•other medicines to treat high blood pressure (hypertension)•medicines called HIV protease inhibitors, such as ritonavir (Norvir®, Kaletra®)•some types of oral antifungals such as ketoconazole (Nizoral®), itraconazole (Sporanox®)•some types of antibiotics such as clarithromycin (Biaxin®), telithromycin (Ketek®), erythromycin (several brand names exist. Please consult your healthcare provider to determine if you are taking this medicine).•other medicines or treatments for ED.•Tadalafil tablets are also marketed as ADCIRCA® for the treatment of pulmonary arterial hypertension. Do not take both sildenafil citrate (Revatio®) with tadalafil tablets.How Should I Take Tadalafil Tablets?•Take tadalafil tablets exactly as your healthcare provider prescribes it. Your healthcare provider will prescribe the dose that is right for you.•Some men can only take a low dose of tadalafil tablets or may have to take it less often, because of medical conditions or medicines they take.•Do not change your dose or the way you take tadalafil tablets without talking to your healthcare provider. Your healthcare provider may lower or raise your dose, depending on how your body reacts to tadalafil tablets and your health condition.•Tadalafil tablets may be taken with or without meals.•If you take too many tadalafil tablets, call your healthcare provider or emergency room right away.How Should I Take Tadalafil Tablets for Symptoms of BPH?For symptoms of BPH, tadalafil tablets are taken once daily.•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet every day at about the same time of day.•If you miss a dose, you may take it when you remember but do not take more than one dose per day.How Should I Take Tadalafil Tablets for ED?For ED, there are two ways to take tadalafil tablets - either for use as needed OR for use once daily.Tadalafil tablets for use as needed:•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet before you expect to have sexual activity. You could get dizzy or faint.•other medicines to treat high blood pressure (hypertension)•medicines called HIV protease inhibitors, such as ritonavir (Norvir®, Kaletra®)•some types of oral antifungals such as ketoconazole (Nizoral®), itraconazole (Sporanox®)•some types of antibiotics such as clarithromycin (Biaxin®), telithromycin (Ketek®), erythromycin (several brand names exist. Please consult your healthcare provider to determine if you are taking this medicine).•other medicines or treatments for ED.•Tadalafil tablets are also marketed as ADCIRCA® for the treatment of pulmonary arterial hypertension. Do not take both sildenafil citrate (Revatio®) with tadalafil tablets.How Should I Take Tadalafil Tablets?•Take tadalafil tablets exactly as your healthcare provider prescribes it. Your healthcare provider will prescribe the dose that is right for you.•Some men can only take a low dose of tadalafil tablets or may have to take it less often, because of medical conditions or medicines they take.•Do not change your dose or the way you take tadalafil tablets without talking to your healthcare provider. Your healthcare provider may lower or raise your dose, depending on how your body reacts to tadalafil tablets and your health condition.•Tadalafil tablets may be taken with or without meals.•If you take too many tadalafil tablets, call your healthcare provider or emergency room right away.How Should I Take Tadalafil Tablets for Symptoms of BPH?For symptoms of BPH, tadalafil tablets are taken once daily.•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet every day at about the same time of day.•If you miss a dose, you may take it when you remember but do not take more than one dose per day.How Should I Take Tadalafil Tablets for ED?For ED, there are two ways to take tadalafil tablets - either for use as needed OR for use once daily.Tadalafil tablets for use as needed:•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet before you expect to have sexual activity.

Before Using

Patient characteristics

You may be able to have sexual activity at 30 minutes after taking tadalafil tablets and up to 36 hours after taking it. You and your healthcare provider should consider this in deciding when you should take tadalafil tablets before sexual activity. Some form of sexual stimulation is needed for an erection to happen with tadalafil tablets.•Your healthcare provider may change your dose of tadalafil tablets depending on how you respond to the medicine, and on your health condition.ORTadalafil tablets for once daily use are a lower dose you take every day.•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet every day at about the same time of day. You may attempt sexual activity at any time between doses.•If you miss a dose, you may take it when you remember but do not take more than one dose per day.•Some form of sexual stimulation is needed for an erection to happen with tadalafil tablets.•Your healthcare provider may change your dose of tadalafil tablets depending on how you respond to the medicine, and on your health condition.How Should I Take Tadalafil Tablets for Both ED and the Symptoms of BPH?For both ED and the symptoms of BPH, tadalafil tablets are taken once daily.•Do not take tadalafil tablets more than one time each day.•Take one tadalafil tablet every day at about the same time of day. You may attempt sexual activity at any time between doses.•If you miss a dose, you may take it when you remember but do not take more than one dose per day.•Some form of sexual stimulation is needed for an erection to happen with tadalafil tablets.What Should I Avoid While Taking Tadalafil Tablets?•Do not use other ED medicines or ED treatments while taking tadalafil tablets.•Do not drink too much alcohol when taking tadalafil tablets (for example, 5 glasses of wine or 5 shots of whiskey). Drinking too much alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.What Are The Possible Side Effects Of Tadalafil Tablets?See “What Is The Most Important Information I Should Know About Tadalafil Tablets?”The most common side effects with tadalafil tablets are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects usually go away after a few hours. Men who get back pain and muscle tadalafil sale aches usually get it 12 to 24 hours after taking tadalafil tablets. Back pain and muscle aches usually go away within 2 days.Call your healthcare provider if you get any side effect that bothers you or one that does not go away.Uncommon side effects include:An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away.

14.3 Tadalafil Tablets 5 mg for Once Daily Use for Benign Prostatic Hyperplasia (BPH)

Product ENTECAVIR / 0,5 mg; 1 mg Tablet

Symptoms of an allergic reaction may include:•rash•hives•swelling of the lips, tongue, or throat•difficulty breathing or swallowingCall your healthcare provider or get help right away if you have any of the symptoms of an allergic reaction listed above.What Should I Tell My Healthcare Provider Before Taking Tadalafil Tablets?Tadalafil tablets are not right for everyone. Only your healthcare provider and you can decide if tadalafil tablets are right for you. Before taking tadalafil tablets, tell your healthcare provider about all your medical problems, including if you:•have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your healthcare provider if it is safe for you to have sexual activity. You should not take tadalafil tablets if your healthcare provider has told you not to have sexual activity because of your health problems.•have pulmonary hypertension•have low blood pressure or have high blood pressure that is not controlled•have had a stroke•have liver problems•have kidney problems or require dialysis•have retinitis pigmentosa, a rare genetic (runs in families) eye disease•have ever had severe vision loss, including a condition called NAION•have stomach ulcers•have a bleeding problem•have a deformed penis shape or Peyronie’s disease•have had an erection that lasted more than 4 hours•have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemiaCan Other Medicines Affect Tadalafil Tablets?Tell your healthcare provider about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Priapism must be treated as soon as possible or lasting damage can happen to your penis, including the inability to have erections.Color vision changes, such as seeing a blue tinge (shade) to objects or having difficulty telling the difference between the colors blue and green.In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including tadalafil tablets) reported a sudden decrease or loss of vision in one or both eyes. It is uncertain whether PDE5 inhibitors directly cause the vision loss. If you experience sudden decrease or loss of vision, stop taking PDE5 inhibitors, including tadalafil tablets, and call a healthcare provider right away.Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been rarely reported in people taking PDE5 inhibitors, including tadalafil tablets.

Aspect	Details
Recommended Dose	5 mg once daily
Timing of Dose	With or without food, same time daily
Missed Dose	Take as soon as remembered, do not double dose
Duration of Use	As prescribed, typically long-term
Overdose	Seek medical attention; symptoms may include headache, dizziness

It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking tadalafil tablets and contact a healthcare provider right away.These are not all the possible side effects of tadalafil tablets. For more information, ask your healthcare provider or pharmacist.How Should I Store Tadalafil Tablets?Store tadalafil tablets at room temperature between 59oF and 86oF (15oC and 30oC).Keep tadalafil tablets and all medicines out of the reach of children.General Information About Tadalafil Tablets:Medicines are sometimes prescribed for conditions other than those described in patient information leaflets.

The medication can be taken with or without food.
Common side effects include headache and flushing.
Consult your doctor before starting tadalafil 5mg.