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In erectile dysfunction (ED), this increases blood flow to penile tissue, facilitating an erection.

• Sildenafil 25 mg tablets are used to treat erectile dysfunction.
• They work by increasing blood flow to the penis.
• Typically taken 30-60 minutes before sexual activity.
• Do not exceed one dose per day to avoid side effects.

In pulmonary arterial hypertension (PAH), it dilates pulmonary vessels by the same mechanism, reducing pulmonary blood pressure and improving exercise capacity.

Country	Average Price (per strip)	Availability	Purchase Options
USA	$8 - $12	Widely available	Pharmacies, online providers
UK	£5 - £10	Common	Over-the-counter, prescription
India	₹50 - ₹150	Readily available	Local pharmacies, online vendors
Australia	AUD 10 - AUD 20	Available	Prescription required

Sildenafil first gained FDA approval on March 27, 1998.

How should I take sildenafil?

Tell your doctor if your condition does not get better. Dizziness, headache, flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Sildenafil Tablets or Oral Suspension for PAH

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Sexual activity may put extra strain on your heart, especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: Rarely, sudden decreased vision, or even permanent blindness, may occur in one or both eyes (NAION). If this serious problem occurs, stop taking sildenafil and get medical help right away.

What’s the difference between sildenafil 50 mg and 100 mg?

You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke. Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur. Rarely, males may have a sildenafil 100mg blue pill painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers".

Product	Dosage	Quantity + Bonus	Price
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Viagra Generic	50mg	10 Pills	26.87€ 25.59€	Buy
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Viagra Generic	200mg	120 + 8 Pills	204.80€ 195.05€	Buy
Viagra Generic	100mg	90 + 6 Pills	129.02€ 122.88€	Buy
Kamagra Polo	100mg	120 + 6 Pills	327.15€ 311.57€	Buy
Viagra Generic	200mg	30 + 2 Pills	83.07€ 79.11€	Buy
Viagra Generic	150mg	120 + 8 Pills	177.58€ 169.12€	Buy

Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

6.2 Postmarketing Experience

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Who Should NOT Take Sildenafil

Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) This drug may make you dizzy or cause vision problems. Alcohol or marijuana (cannabis) can make you more dizzy.

Dosage Modifications

Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, sildenafil should be used only when clearly needed. Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. Some medicines can cause unwanted or dangerous effects when used with sildenafil.

What should I know about storage and disposal of this medication?

Canada residents can call 1-844-764-7669. Symptoms of overdose may include: severe dizziness, fainting, painful/prolonged erection. Do not share this medication with others. Store at room temperature away from light and moisture. Keep all medications away from children and pets.

Does sildenafil interact with other medicines (drug interactions)?

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you.

Regional issues

This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019. This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. Tell your doctor about all your current medicines, especially riociguat (Adempas).

• The onset of effect usually occurs within 30 minutes to 1 hour.
• The effects can last up to 4-6 hours, depending on the individual.
• Patients should avoid heavy meals before taking the medication.
• Sildenafil 25 mg is available by prescription only in most countries.

The most common side effects of sildenafil tablets for ED are: Abnormal vision, such as changes in color vision (such as having a blue color tinge) andblurred vision The most common side effects of sildenafil oral film for ED are: Abnormal vision, such as changes in color and blurred vision The most common side effects of sildenafil tablets/ oral suspension, and injection for PAH are: Sildenafil can cause the following serious side effects.

• Consult your doctor if you experience vision changes or ringing in ears.
• Sildenafil can interact with nitrates, causing dangerous hypotension.
• Use with caution if you have heart problems or low blood pressure.
• Report any persistent or painful erections lasting over 4 hours.

If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis.

Side Effect	Incidence	Severity	Management Suggestions
Headache	Common	Mild to moderate	Take pain relievers
Flushing	Common	Mild	Cool compress, hydration
Dizziness	Common	Mild	Sit or lie down immediately
Nasal Congestion	Less common	Mild	Use decongestants if needed
Visual Disturbances	Rare	Mild	Discontinue and consult doctor

Sildenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss.

Detection in biological fluids

You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. Pronunciation: sil-DEN-a-fil Generic name: sildenafil Brand names: Revatio, Viagra, Vybrique Dosage form: tablets (20 mg; 25 mg, 50 mg, 100 mg), injection (10 mg/12.5 mL), oral suspension (10 mg/mL), oral film (25 mg, sildenafil price ireland 50 mg, 75 mg, 100 mg) Drug classes: Agents for pulmonary hypertension, Impotence medications Sildenafil is used to treat erectile dysfunction (ED) in adult men or pulmonary arterial hypertension (PAH) in adults and children, depending on the brand or formulation. Sildenafil tablets (25 mg, 50 mg, 100 mg; Viagra, generic) and sildenafil oral film (25 mg, 50 mg, 75 mg, 100 mg; Vybrique) are used for ED. Sildenafil tablets (20 mg; Revatio, generic), sildenafil oral suspension (Revatio, generic), and sildenafil injection (Revatio, generic) are used for PAH. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, which breaks down cyclic GMP and enhances nitric oxide (NO) -mediated smooth muscle relaxation. This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old.

• Sildenafil 25 mg has a rapid onset compared to higher doses.
• It is considered effective for most men with mild to moderate ED.
• Alcohol intake can reduce the effectiveness of the medication.
• The medication is generally safe when used as directed by a healthcare provider.

Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION).

Food Type	Effect on Absorption	Interaction with Alcohol	Clinical Significance
High-fat meals	Delays absorption	No direct interaction	Typically prolongs onset time
Alcohol consumption	No significant effect (modest amounts)	Can enhance side effects like dizziness, hypotension	Moderate intake is generally safe, excessive alcohol can impair efficacy
Light meal	Minimal effect	None	Safe to take with meals

Stop taking sildenafil and call your healthcare provider right away if you havesudden vision loss in one or both eyes.

Are erectile dysfunction medicines safe?

If you are planning pregnancy, become pregnant, or think you may be pregnant, discuss with your doctor right away the benefits and risks of using this medication during pregnancy. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Does sildenafil cause different side effects in females?

Some products that may interact with this drug are: Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure. Other medications can buy pills sildenafil affect the removal of sildenafil from your body, which may affect how sildenafil works.

How does sildenafil work (mechanism of action)?

Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), mifepristone, rifampin, ritonavir, among others. Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call 1-800-222-1222.